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Studies of the microbiome in the human gut focus mainly on bacteria. Other microbes that are also present in the gut — viruses, protists, archaea, and fungi — have been largely overlooked. New research in mice now points to a significant role for fungi in the intestine — the communities of molds and yeasts known […]

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A team of researchers co-led by Michael Frohman, MD, PhD, of Stony Brook University, has identified an important cause of congenital heart disease. They discovered that certain loss of functions in the PLD1 (Phospholipase D1) gene causes congenital right-sided cardiac valve defects and neonatal cardiomyopathy. Their findings are detailed in a paper published early online […]

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An open-source platform, OpenEP co-developed by researchers from the School of Biomedical Engineering & Imaging Sciences at King's College London has been made available to advance research on atrial fibrillation, a condition characterized by an irregular and often fast heartbeat. It can cause significant symptoms such as breathlessness, palpitations and fatigue, as well as being […]

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Clinical research requires that data be mined for insights. Machine learning, which develops algorithms to find patterns, has difficulty doing this with data related to health records because this type of information is neither static nor regularly collected. A new study developed a transparent and reproducible machine learning tool to facilitate analysis of health information. […]

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the novel virus behind the ongoing coronavirus disease 2019 (COVID-19) pandemic that has already claimed over 2.5 million lives globally. A key priority of COVID-19 research is understanding the kinetics and the protective role of the antibody response to SARS-CoV-2 in the affected population. It is also […]

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The first instance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in Austria was observed in the Ski resort Ischgl in early March 2020. Later, the virus spread across Austria and other countries in Northern Europe. Researchers conducted a cross-sectional study to gauge the seroprevalence of SARS-CoV-2 in the population, as measured in […]

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The coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread worldwide. To date, more than 112.5 million people have been infected, with over 2.49 million deaths lost to COVID-19. The United States is one of the countries hardest hit by the pandemic, with the number of infections skyrocketing […]

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Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations. The origin of this disease has been associated with the anomalous functioning of the mutated protein: mHTT, but recent data showed the involvement of other molecular mechanisms. A new study conducted by […]

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HSE University researchers have become the first in the world to discover genetic predisposition to severe COVID-19. The results of the study were published in the journal Frontiers in Immunology. T-cell immunity is one of the key mechanisms used by the human body to fight virus infections. The staging ground for cell immunity development is […]

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England's salt reduction programme will have led to nearly 200,000 fewer adults developing heart disease and £1.64 billion of healthcare cost savings by 2050, according to research by Queen Mary University of London. However, the researchers warn that the recent stalling of salt reduction programmes is endangering the potential health gains, as salt intake remains […]