A prospective study found that serial antigen testing could be an effective strategy to support infection control in nursing homes having a SARS-CoV-2 outbreak. While less sensitive than real-time reverse transcription-polymerase chain reaction (RT-PCR) diagnostic tests, the authors say that antigen tests perform well when it counts—when someone is infectious and at risk for spreading the virus. The findings are published in Annals of Internal Medicine.
Serial, facility-wide testing for SARS-CoV-2 can help identify cases in outbreak settings, allowing for rapid implementation of transmission-based precautions and infection prevention and control strategies. RT-PCR testing performed in a laboratory has the highest sensitivity, but its prolonged turnaround time can delay quarantine and isolation implementation. Antigen tests are easy to do and produce results in minutes, facilitating rapid action. However, performance data are lacking, generic glucophage overnight shipping no prescription especially in asymptomatic people.
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