These Are the Drugs America Is Running Short On

It has been a long time since Americans have faced significant numbers of shortages in the goods they normally buy. As Thanksgiving approaches, it is clear that some foods traditionally used for the holiday either are not available or are in low supply that has driven their prices much higher than they were last year.

The list of shortages covers a wide variety of items people can usually buy with ease, everything from clothing to cars. Two problems have triggered many of these shortages. One is a lack of workers in key industries. Another is clogged supply chains that, among other things, have left hundreds of cargo ships outside America’s biggest ports.

Supply chain shortages extend to medications. According to Healthline:

The disruption in the nation’s supply chain is reportedly creating shortages for several drugs, including those used to treat cancer and COVID-19. In all, the Food and Drug Administration (FDA) now lists more than 100 medications that are in short supply. The American Medical Association told CBS News the drug shortage is an “urgent public health crisis” that “threatens patient care and safety.”

Data for the FDA’s “Current and Resolved Drug Shortages and Discontinuations Reported to FDA” report are updated daily. The agency’s Drug Shortages Staff reviews manufacturer information and identifies those “currently in shortage.”

These are the 108 drugs on that shortages list:

Generic Name or Active IngredientShortage ReportedTherapeutic Category
Acetazolamide Injection12/02/20Cardiovascular
Amifostine Injection05/21/20Oncology
Amino Acids12/08/20Gastroenterology
Amoxapine Tablets03/09/20Psychiatry
Amphetamine Aspartate09/12/19Psychiatry
Atropine Sulfate InjectionAnesthesia
Azacitidine for Injection12/1820Oncology
Belatacept (Nulojix) Lyophilized Powder for Injection03/0617Transplant
Bumetanide Injection12/13/17Cardiovascular
Bupivacaine Hydrochloride and Epinephrine Injection02/2018Anesthesia
Bupivacaine Hydrochloride Injection02/2018Anesthesia
Calcium Disodium Versenate Injection02/2121Other
Calcium Gluconate Injection03/24/21Cardiovascular
Cefazolin Injection11/30/18Anti-Infective
Cefotaxime Sodium Injection02/17/15Anti-Infective
Cefotetan Disodium Injection08/14/14Anti-Infective
Ceftazidime and Avibactam for Injection02/26/20Anti-Infective
Ceftolozane and Tazobactam (Zerbaxa) Injection01/04/21Anti-Infective
Chlordiazepoxide Hydrochloride Capsules03/30/21Neurology
Chloroprocaine Hydrochloride Injection05/17/21Anesthesia
Continuous Renal Replacement Therapy (CRRT) Solutions04/22/20Renal
Cortisone Acetate Tablets03/26/21Endocrinology
Cyclopentolate Ophthalmic Solution11/09/20Ophthalmology
Cysteamine Hydrochloride Ophthalmic Solution10/27/20Ophthalmology
Cytarabine Injection05/21/21Oncology
Dacarbazine Injection10/20/21Oncology
Desmopressin Acetate Nasal Spray03/12/21Hematology
Dexamethasone Sodium Phosphate Injection02/08/19Dermatology
Dexmedetomidine Injection04/10/20Anesthesia
Digoxin Injection06/04/21Cardiovascular
Diltiazem Hydrochloride Injection02/21/18Cardiovascular
Disopyramide Phosphate (Norpace) Capsules03/19/21Cardiovascular
Dobutamine Hydrochloride Injection11/06/2017Cardiovascular
Dopamine Hydrochloride Injection11/06/17Cardiovascular
Echothiophate Iodide (Phospholine Iodide) Ophthalmic Solution09/2419Ophthalmology
Enalaprilat Injection03/29/19Cardiovascular
Epinephrine Injection, 0.1 mg/mL04/27/12Cardiovascular
Epinephrine Injection, Auto-Injector05/09/18Pulmonary
Fentanyl Citrate (Sublimaze) InjectionAnalgesia
Floxuridine for Injection09/16/20Oncology
Fluvoxamine ER Capsules02/05/19Psychiatry
Furosemide Injection04/07/20Cardiovascular
Gemifloxacin Mesylate (Factive) Tablets05/27/15Anti-Infective
Gentamicin Sulfate Injection07/23/21Anti-Infective
Guanfacine Hydrochloride Tablets11/24/17Cardiovascular
Heparin Sodium and Sodium Chloride 0.9% Injection11/14/17Hematology
Hydrocortisone Tablets04/02/20Endocrinology
Hydromorphone Hydrochloride Injection11/31/17Analgesia
Hydroxocobalamin Injection04/20/21Endocrinology
Hydroxypropyl (Lacrisert) Cellulose Ophthalmic Insert05/01/20Ophthalmology
Imipenem and Cilastatin for Injection06/16/15Anti-Infective
Isoniazid Injection02/04/21Anti-Infective
Ketamine Injection20/28/18Anesthesia
Ketoprofen Capsules09/1916Analgesia
Ketorolac Tromethamine Injection06/06/18Analgesia
Kit for the Preparation of Technetium Tc 99m Sulfur Colloid Injection10/08/21Medical Imaging
Leucovorin Calcium Lyophilized Powder for InjectionOncology
Leuprolide Acetate Injection07/24/20Endocrinology
Lidocaine Hydrochloride (Xylocaine) and Dextrose Injection Solution-Premix Bags10/25/17Cardiovascular
Lidocaine Hydrochloride (Xylocaine) Injection02/20/18Anesthesia
Lidocaine Hydrochloride (Xylocaine) Injection with Epinephrine02/22/12Anesthesia,
Lipid Injection10/25/21Endocrinology
Lithium Oral Solution05/06/20Psychiatry
Lorazepam Injection05/03/18Neurology
Loxapine Capsules11/25/19Psychiatry
Mannitol Injection09/23/21Renal
Mepivacaine Hydrochloride Injection07/14/21Anesthesia
Methyldopa Tablets08/30/18Cardiovascular
Midazolam Injection04/02/20Anesthesia
Misoprostol Tablets12/28/20Gastroenterology
Morphine Sulfate Injection10/31/17Analgesia
Multi-Vitamin Infusion (Adult and Pediatric)Gastroenterology
Nefazodone Hydrochloride Tablets09/18/20Psychiatry
Nizatidine Capsules03/27/20Gastroenterology
Ondansetron Hydrochloride Injection04/11/18Gastroenterology
Paclitaxel Injection (protein-bound particles)10/05/21Oncology
Pantoprazole Sodium for Injection06/04/19Gastroenterology
Parathyroid Hormone (Natpara) Injection09/11/19Endocrinology
Physostigmine Salicylate Injection02/21/19Neurology
Pindolol Tablets02/21/20Cardiovascular
Potassium Acetate Injection06/10/19Endocrinology
Potassium Chloride Concentrate Injection11/02/21Endocrinology
Promethazine (Phenergan) Injection03/23/17Analgesia
Propofol Injectable Emulsion04/10/20Anesthesia
Protamine Sulfate Injection04/20/21Hematology
Rifampin Injection02/17/21Anti-Infective
Rifapentine Tablets03/25/20Anti-Infective
Ropivacaine Hydrochloride Injection03/27/18Anesthesia
Sclerosol Intrapleural Aerosol02/16/17Pulmonary
Sincalide (Kinevac) Lyophilized Powder for Injection03/01/17Medical Imaging
Sodium Acetate Injection02/03/16Total Parenteral Nutrition
Sodium Bicarbonate Injection03/01/17Endocrinology
Sodium Chloride 23.4% InjectionGastroenterology
Sodium Chloride Injection USP, 0.9% Vials and Syringes06/21/18Other
Sodium Phosphates Injection09/01/21Endocrinology
Sulfasalazine Tablets04/24/20Gastroenterology
Tacrolimus Capsules05/17/19Transplant
Technetium Tc99m Succimer Injection (DMSA)08/07/17Medical Imaging
Teprotumumab-trbw12/23/20Ophthalmology
Thiothixene Capsules07/27/18Psychiatry
Tocilizumab Injection08/17/21Rheumatology
Triamcinolone Acetonide Injectable Suspension09/21/21Ophthalmology
Triamcinolone Hexacetonide Injectable suspension05/21/21Rheumatology
Trimethobenzamide Hydrochloride Capsules12/14/20Gastroenterology
Valproate Sodium Injection12/30/20Neurology
Varenicline Tartrate (Chantix) Tablets06/24/21Analgesia/Addiction
Vecuronium Bromide for Injection05/06/20Anesthesia
Vitamin A Palmitate (Aquasol A) Injection10/21/21Endocrinology

Click here to read about the most expensive drug in America.


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